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. Author manuscript; available in PMC: 2013 Jun 19.
Published in final edited form as: Int J Comput Healthc. 2012 Jan 1;1(3):214–228. doi: 10.1504/IJCIH.2012.046995

Figure 1. Simplified interaction between the critical influencing elements associated with ECM synthesis (+ influence) and degradation (− influence).

Figure 1

Note: The modelling approach here characterises the dynamic influence of growth factors and cytokines through a direct mathematical link with chondrocyte behaviour.