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. Author manuscript; available in PMC: 2013 Jun 19.
Published in final edited form as: Int J Comput Healthc. 2012 Jan 1;1(3):214–228. doi: 10.1504/IJCIH.2012.046995

Table 1. The roles and responsibilities of the primary biomolecules within articular cartilage.

Chondrocytes and extracellular matrix

Collagen Structural protein Proteoglycans Core protein Growth factors Other proteins
Overall mechanical integrity Swelling tendency Regulate cellular behaviour
Stiffness influence Compression resistance
Tensile resistance Lubrication
Shear resistance