Table 3.

Estimates of main and interaction effects for environmental and genetic risk factors from the most parsimonious model, white ever smoking women (Model 2)

	OR (95% CI)	p-value
Family history of lung cancer	2.30 (1.24–4.27)	0.0083
History of chronic obstructive lung disease	1.91 (1.12–3.26)	0.0169
Pack years of cigarette smoking	1.02 (1.01–1.04)	<.0001
Body mass index (BMI)	0.71 (0.57–0.89)	0.0032
Education	0.39 (0.23–0.65)	0.0003
GSTM1 null	19.1 (1.91–191)	0.0121
XRCC1 A/A genotype	1.94 (1.01–3.75)	0.0483
GSTP1 A/A or A/G genotype	2.31 (1.15–4.64)	0.0181
BMI and Education	1.02 (1.01–1.04)	0.0051
BMI and GSTM1	0.91 (0.84–0.99)	0.0213
Smoking and Education	1.004 (1.00–1.01)	0.0323