With the test set built by Wang,25 binding affinity comparison was done for KECSA, LISA, LISA+ and several other well-known scoring functions, ITScore/SE,18 ITScore,17 X-Score,26 DFIRE,27 DrugScoreCSD,12 DrugScorePDB,11 Cerius2/PLP,28,29 SYBYL/G-Score,30 SYBYL/D-Score,31 SYBYL/ChemScore,32 Cerius2/PMF,8 DOCK/FF,31 Cerius2/LUDI,33,34 Cerius2/LigScore,35 SYBYL/F-Score,36 AutoDock.37