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Key milestones in the lifecourse of osteoporosis therapy. Strontium ranelate is not approved by the FDA but all other agents have been approved both by the FDA and EMA.
Note: The dates shown represent the year that they were first approved by the FDA (or EMA for strontium ranelate) for use in the treatment of osteoporosis.
Abbreviations: EMA, European Medicines Agency; FDA, US Food and Drug Administration; IV, intravenous.
