Correlations between (poly)unsaturated fatty acid concentrations in erythrocyte membranes and white matter (WM) fractional anisotropy in 30 patients with a recent-onset psychotic disorder.
Top panel: Significant correlation between total (poly)unsaturated fatty acid concentration and fractional anisotropy in a large WM cluster comprised of 16 441 voxels, centered in the corpus callosum and extending into parietal, occipital, temporal and frontal WM (r
s = 0.636, P < 0.001).
Bottom panel: Significant correlation between arachidonic acid concentration and fractional anisotropy in a large WM cluster comprised of 5 950 voxels, centered in the corpus callosum and extending into parietal, occipital, temporal and frontal WM (r
s = 0.544, P = 0.002).