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. Author manuscript; available in PMC: 2014 May 17.
Published in final edited form as: J Org Chem. 2013 Apr 29;78(10):4744–4761. doi: 10.1021/jo400222c

Figure 6.

Figure 6

Protodepalladation as monitored by 1H NMR spectroscopy (Substrate = 7). Compound 6 was mixed with Pd(O2CCF3)2 in 0.75 mL DMSO-d6 and heated to 80 °C for 1 h. After cooling, a 1H NMR spectrum was taken, CH3SO3H was added, and 1H NMR monitoring was continued at 65 °C. Reaction conditions: initial concentration [6] = 0.08 M and [Pd(O2CCF3)2] = 0.10 M, 10 equiv CH3SO3H, 0.75 mL DMSO-d6. Equation of the line for b is y = 0.048x – 2.424. R2 = 0.998.