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. Author manuscript; available in PMC: 2013 Jun 19.
Published in final edited form as: Gene Ther. 2010 Dec 9;18(4):403–410. doi: 10.1038/gt.2010.157

Fig. 3.

Fig. 3

Reduction in liver expression of luciferase resulting from incorporation of the liver-specific miRNA target sequence miR-122T into AAV9 vectors containing the luciferase reporter gene. AAV9-CB-Luc vectors with or without the miR-122 target sequence were injected into the tail veins of 6-wk-old female ICR mice (1×1012 vg/mouse, n=5). After 3 weeks, there was no difference between luciferase expression of TA muscles, 50-fold lower expression in miR-122T liver (**, p<0.01), and significantly higher expression in miR-122T heart (*, p<0.05). Error bars indicated standard deviation.