Table 5.
Factors Associated with Increased Risk of Mortality
| Univariate | Multivariate | |||
|---|---|---|---|---|
| HR (95% CI) | p | HR (95% CI) | p | |
| Female Gender | 1.004 (0.42–2.39) | 0.99 | ||
| Nonwhite race | * | 0.14 | ||
| Cancer | ||||
| Lymphoma | Ref | 0.09 | ||
| Colorectal | 0.90 (0.33–2.40) | |||
| Breast | * | |||
| Lung | 3.99 (1.23–12.92) | |||
| Living Situation | ||||
| Single Family | Ref | 0.59 | ||
| Nursing | 2.048 (0.27–15.45) | |||
| Independent | * | |||
| Caregiver | 1.61 (0.47–5.48) | 0.45 | ||
| Falls | 2.99 (1.06–8.42) | 0.039 | 3.20 (1.13–9.11) | 0.029 |
| Intent (curative vs palliative) | 0.16 (0.06–0.43) | <0.001 | 0.15 (0.06–0.42) | <0.001 |
| Depression | 1.28 (0.49–3.34) | 0.62 | ||
| ADL dependence | 0.38 (0.051–2.86) | 0.35 | ||
| IADL dependence | 2.00 (0.85–4.75) | 0.11 | ||
| Cognitive impairment | 0.83 (0.11–6.23) | 0.86 | ||
| ECOG PS 2–3 | 1.74 (0.58–5.23) | 0.32 | ||
| Comorbidities (moderate-severe) | 1.70 (0.71–4.06) | 0.23 | ||
| Anemia | 0.40 (0.58–3.86) | 0.70 | ||
| Age | 1.06 (0.00–1.13) | 0.099 | ||
| Body Mass Index | 0.96 (0.89–1.04) | 0.29 | ||
| Creatinine clearance | 0.99 (0.97–1.01) | 0.21 |
*
Not estimable due to 0 count of mortality in the cell
HR, Hazard ratio; CI, confidence intervals; ADL, activities of daily living; IADL, instrumental activities of daily living; ECOG PS, Eastern Cooperative Oncology Group Performance Status; CrCl, creatinine clearance.