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. Author manuscript; available in PMC: 2014 Jul 1.
Published in final edited form as: Tuberculosis (Edinb). 2013 May 4;93(4):398–400. doi: 10.1016/j.tube.2013.04.002

Table 1.

Biological data for compounds 1 and 3.a

Compounds Mtb FtsZ Polymerizationb ID50 (μM) Tubulin Polymerizationb ID50 (μM) Mtb H37Rv IC90 (μM) Vero Cytotoxicity CC50 (μM)
1 22.7 ± 0.4 >100 μM 20.4 >120
3 >100 μM 5.4 ± 0.1 15.7 <0.2
a

Methods are reported in references 4 and 9.

b

Each compound was analyzed at least three times per assay. For the polymerization assays, the mean ± the standard deviations are reported.