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A, Examples of traces showing the amplitudes of tonic GABA currents in D1- and D2-expressing MSNs from WT and R6/2 mice. Recordings were in the presence of CNQX (10 μm), AP-5 (50 μm), and CGP (1 μm). The arrow in each trace represents the time when BIC (20 μm) was added. B, Tonic GABA current amplitudes were significantly reduced only in D2 receptor-expressing MSNs from R6/2 mice.
