Table 1.
Reported and rearranged data from MS incidence surveys presented in Figure3
|
Study |
|
Men |
Women |
Both |
||||||
|---|---|---|---|---|---|---|---|---|---|---|
| First author Reference | Age group | Cases | Person-years | Rate | Cases | Person-years | Rate | Cases | Person-years | Rate |
| Debouverie 2007
[31] |
0-14 |
0 |
3,070,347 |
0.00 |
7 |
2,911,480 |
0.24 |
7 |
5,981,827 |
0.12 |
| 15-24 |
59 |
2,191,949 |
2.69 |
213 |
2,072,309 |
10.28 |
272 |
4,264,258 |
6.38 |
|
| 25-34 |
154 |
2,236,211 |
6.89 |
445 |
2,199,900 |
20.23 |
599 |
4,436,111 |
13.50 |
|
| 35-44 |
151 |
2,262,937 |
6.67 |
339 |
2,249,492 |
15.07 |
490 |
4,512,429 |
10.86 |
|
| 45-54 |
93 |
1,827,995 |
5.09 |
137 |
1,782,369 |
7.69 |
230 |
3,610,364 |
6.37 |
|
| 55-64 |
21 |
1,458,543 |
1.44 |
32 |
1,542,168 |
2.08 |
53 |
3,000,711 |
1.77 |
|
| 65+ |
2 |
1,680,520 |
0.12 |
5 |
2,584,219 |
0.19 |
7 |
4,264,739 |
0.16 |
|
| Guidetti 1995
[36] |
0-14 |
0 |
449,088 |
0.00 |
0 |
428,838 |
0.00 |
0 |
877,926 |
0.00 |
| 15-24 |
12 |
437,867 |
2.74 |
20 |
424,286 |
4.71 |
32 |
862,153 |
3.71 |
|
| 25-34 |
7 |
429,913 |
1.63 |
25 |
425,059 |
5.88 |
32 |
854,972 |
3.74 |
|
| 35-44 |
9 |
420,283 |
2.14 |
16 |
419,570 |
3.81 |
25 |
839,853 |
2.98 |
|
| 45-54 |
1 |
407,265 |
0.25 |
11 |
409,216 |
2.69 |
12 |
816,481 |
1.47 |
|
| 55-64 |
0 |
384,447 |
0.00 |
2 |
416,345 |
0.48 |
2 |
800,792 |
0.25 |
|
| 65+ |
0 |
414,027 |
0.00 |
0 |
595,139 |
0.00 |
0 |
1,009,166 |
0.00 |
|
| Alonso 2007
[48] |
0-14 |
0 |
1,114,646 |
0.00 |
0 |
1,061,240 |
0.00 |
0 |
2,175,886 |
0.00 |
| 15-24 |
6 |
711,643 |
0.84 |
24 |
700,702 |
3.43 |
30 |
1,412,345 |
2.12 |
|
| 25-34 |
50 |
928,136 |
5.39 |
115 |
926,436 |
12.41 |
165 |
1,854,572 |
8.90 |
|
| 35-44 |
57 |
860,894 |
6.62 |
155 |
837,502 |
18.51 |
212 |
1,698,396 |
12.48 |
|
| 45-54 |
51 |
800,963 |
6.37 |
111 |
780,853 |
14.22 |
162 |
1,581,816 |
10.24 |
|
| 55-64 |
29 |
592,600 |
4.89 |
31 |
596,522 |
5.20 |
60 |
1,189,122 |
5.05 |
|
| 65+ |
5 |
754,786 |
0.66 |
8 |
1,078,718 |
0.74 |
13 |
1,833,504 |
0.71 |
|
| Nicoletti 2005
[32] |
0-14 |
2 |
297,120 |
0.67 |
1 |
281,850 |
0.35 |
3 |
578,970 |
0.52 |
| 15-24 |
10 |
251,490 |
3.98 |
19 |
246,740 |
7.70 |
29 |
498,230 |
5.82 |
|
| 25-34 |
22 |
237,360 |
9.27 |
34 |
240,670 |
14.13 |
56 |
478,030 |
11.71 |
|
| 35-44 |
12 |
205,920 |
5.83 |
25 |
226,150 |
11.05 |
37 |
432,070 |
8.56 |
|
| 45-54 |
7 |
177,620 |
3.94 |
17 |
203,130 |
8.37 |
24 |
380,750 |
6.30 |
|
| 55-64 |
3 |
158,980 |
1.89 |
3 |
193,760 |
1.55 |
6 |
352,740 |
1.70 |
|
| 65+ |
0 |
205,740 |
0.00 |
0 |
295,230 |
0.00 |
0 |
500,970 |
0.00 |
|
| Joensen 2010
[40] |
0-14 |
0 |
125,615 |
0.00 |
0 |
118,653 |
0.00 |
0 |
244,268 |
0.00 |
| 15-24 |
3 |
81,263 |
3.69 |
6 |
69,516 |
8.63 |
9 |
150,779 |
5.97 |
|
| 25-34 |
5 |
74,267 |
6.73 |
9 |
63,934 |
14.08 |
14 |
138,201 |
10.13 |
|
| 35-44 |
6 |
75,305 |
7.97 |
5 |
66,389 |
7.53 |
11 |
141,694 |
7.76 |
|
| 45-54 |
3 |
64,103 |
4.68 |
5 |
55,218 |
9.06 |
8 |
119,321 |
6.70 |
|
| 55-64 |
0 |
49,604 |
0.00 |
1 |
44,487 |
2.25 |
1 |
94,091 |
1.06 |
|
| 65+ |
0 |
59,298 |
0.00 |
1 |
71,896 |
1.39 |
1 |
131,194 |
0.76 |
|
| Sundstrom 2003
[37] |
0-14 |
1 |
255,257 |
0.40 |
1 |
244,079 |
0.40 |
2 |
499,336 |
0.40 |
| 15-24 |
5 |
175,802 |
2.90 |
14 |
169,431 |
8.40 |
19 |
345,233 |
5.60 |
|
| 25-34 |
18 |
179,111 |
10.00 |
32 |
166,142 |
19.20 |
50 |
345,253 |
14.40 |
|
| 35-44 |
16 |
182,644 |
8.70 |
23 |
171,520 |
13.40 |
39 |
354,164 |
10.90 |
|
| 45-54 |
7 |
163,908 |
4.20 |
12 |
157,093 |
7.50 |
19 |
321,001 |
5.90 |
|
| 55-64 |
0 |
126,402 |
0.00 |
4 |
131,128 |
3.10 |
4 |
257,530 |
1.60 |
|
| 65+ |
0 |
189,679 |
0.00 |
0 |
239,325 |
0.00 |
0 |
429,004 |
0.00 |
|
| Granieri 2007
[34] |
0-14 |
0 |
247,388 |
0.00 |
2 |
232,900 |
0.86 |
2 |
480,288 |
0.42 |
| 15-24 |
10 |
282,723 |
3.54 |
17 |
267,370 |
6.36 |
27 |
550,093 |
4.91 |
|
| 25-34 |
21 |
370,041 |
5.68 |
55 |
353,479 |
15.56 |
76 |
723,520 |
10.50 |
|
| 35-44 |
13 |
348,169 |
3.73 |
41 |
349,768 |
11.72 |
54 |
697,937 |
7.74 |
|
| 45-54 |
8 |
336,728 |
2.38 |
18 |
350,939 |
5.13 |
26 |
687,667 |
3.78 |
|
| 55-64 |
1 |
331,387 |
0.30 |
4 |
366,978 |
1.09 |
5 |
698,365 |
0.72 |
|
| 65+ |
0 |
443,139 |
0.00 |
2 |
656,512 |
0.30 |
2 |
1,099,651 |
0.18 |
|
| Granieri 2008
[35] |
0-14 |
0 |
31,856 |
0.00 |
0 |
28,859 |
0.00 |
0 |
60,708 |
0.00 |
| 15-24 |
2 |
25,489 |
7.85 |
4 |
24,735 |
16.17 |
6 |
50,196 |
11.95 |
|
| 25-34 |
3 |
35,513 |
8.45 |
11 |
40,625 |
27.08 |
14 |
76,022 |
18.42 |
|
| 35-44 |
0 |
32,290 |
0.00 |
5 |
33,221 |
15.05 |
5 |
65,509 |
7.63 |
|
| 45-54 |
2 |
27,336 |
7.32 |
2 |
27,582 |
7.25 |
4 |
54,887 |
7.29 |
|
| 55-64 |
1 |
22,396 |
4.47 |
2 |
22,356 |
8.95 |
3 |
44,736 |
6.71 |
|
| 65+ |
0 |
27,157 |
0.00 |
1 |
36,490 |
2.74 |
1 |
63,483 |
1.58 |
|
| Nicoletti 2010
[10] |
0-14 |
0 |
129,630 |
0.00 |
0 |
122,860 |
0.00 |
0 |
252,490 |
0.00 |
| 15-24 |
3 |
103,300 |
2.90 |
13 |
101,785 |
12.77 |
16 |
205,085 |
7.80 |
|
| 25-34 |
10 |
115,110 |
8.69 |
27 |
114,755 |
23.53 |
37 |
229,865 |
16.10 |
|
| 35-44 |
11 |
104,500 |
10.53 |
20 |
114,380 |
17.49 |
31 |
219,880 |
14.10 |
|
| 45-54 |
11 |
98,320 |
11.19 |
8 |
105,025 |
7.62 |
19 |
198,345 |
9.58 |
|
| 55-64 |
4 |
76,320 |
5.24 |
1 |
91,740 |
1.09 |
5 |
168,060 |
2.98 |
|
| 65+ |
0 |
111,475 |
0.00 |
0 |
167,980 |
0.00 |
0 |
275,855 |
0.00 |
|
| Cabre 2009
[8] |
0-14 |
1 |
1,388,049 |
0.07 |
2 |
1,351,144 |
0.15 |
3 |
2,739,193 |
0.11 |
| 15-24 |
6 |
848,215 |
0.71 |
17 |
837,479 |
2.03 |
23 |
1,685,694 |
1.36 |
|
| 25-34 |
8 |
808,481 |
0.99 |
35 |
926,145 |
3.78 |
43 |
1,734,626 |
2.48 |
|
| 35-44 |
7 |
814,933 |
0.86 |
30 |
931,847 |
3.22 |
37 |
1,746,780 |
2.12 |
|
| 45-54 |
2 |
608,781 |
0.33 |
18 |
699,425 |
2.57 |
20 |
1,308,206 |
1.53 |
|
| 55-64 |
1 |
447,677 |
0.22 |
2 |
511,278 |
0.39 |
3 |
958,955 |
0.31 |
|
| 65+ | 0 | 530,373 | 0.00 | 1 | 731,100 | 0.14 | 1 | 1,261,473 | 0.08 | |