Table 2.
Summary of genes and SNPs identified by further literature search as positively correlated with various cancers
|
Gene |
Cancer type |
SNPs |
References |
|
|---|---|---|---|---|
| rs number | Other name | |||
|
CCND1 |
OC |
rs603965 |
c.870G>A |
[26,122-124] |
|
CCND1 |
PC |
rs603965 |
c.870G>A |
[125] |
|
CYP2E1 |
PC |
NA |
NA |
[126] |
|
CYP2E1 |
LC |
NA |
NA |
[127] |
|
CYP2E1 |
UBC |
NA |
NA |
[128] |
|
CYP2E1 |
OC |
NA |
NA |
[40] |
|
ERCC2 |
OC |
rs1799793, rs13181 |
p.D312N, p.K751Q |
[23] |
|
ERCC2 |
HNC |
rs1799793, rs13181 |
p.D312N, p.K751Q |
[129-131] |
|
GSTP1 |
PC |
rs1695 |
p.I105V |
[126,128,132,133] |
|
MTHFR |
BCC |
rs1801131 |
c.677C>T, c.1298A>C |
[134] |
|
MTHFR |
ALL |
rs1801131 |
c.677C>T, c.1298A>C |
[59,135,136] |
|
MTHFR |
LC |
rs1801131 |
c.677C>T, c.1298A>C |
[137] |
|
MTHFR |
UBC |
rs1801131 |
c.677C>T, c.1298A>C |
[138] |
|
MTHFR |
CC |
rs1801131 |
c.677C>T, c.1298A>C |
[139] |
|
MTHFR |
NHL |
rs1801131 |
c.677C>T, c.1298A>C |
[140,141] |
|
MTHFR |
HNC |
rs1801131 |
c.677C>T, c.1298A>C |
[142] |
|
TGFB1 |
GC |
rs1982073 |
c.+29C>T |
[143] |
|
TGFB1 |
LC |
rs1982073 |
c.+29C>T |
[144] |
|
TGFB1 |
PC |
rs1982073 |
c.+29C>T |
[145] |
|
TGFB1 |
PC |
rs1982073 |
c.+29C>T |
[146] |
|
TGFB1 |
CRC |
rs1982073 |
c.+29C>T |
[147] |
|
TP53 |
EmCa |
rs1042522/rs17878362 |
p.R72P |
[148] |
|
TP53 |
PC |
rs1042522/rs17878362 |
p.R72P |
[114,149] |
|
TP53 |
OVCa |
rs1042522/rs17878362 |
p.R72P |
[150] |
|
TP53 |
GC |
rs1042522/rs17878362 |
p.R72P |
[151] |
| TP53 | OC | rs1042522/rs17878362 | p.R72P | [152] |
NA not available.