Table 3.
Putative gene-gene associations with various cancer types
|
Gene associations |
Considered phenotypes |
Comments |
STRING confirmation |
Literature confirmation |
|
|---|---|---|---|---|---|
| Gene 1 | Gene 2 | ||||
|
GSTP1 |
GSTM1 |
4 |
|
Binding interaction |
[Reference]: study type |
|
TGFB1 |
IL6 |
5 |
4 of 5 based on ‘yes’ |
|
|
|
MMP2 |
EGF |
3 |
Based on ‘yes’ |
Activating interaction |
|
|
VEGFA |
IL1B |
2 |
|
Activating interaction |
|
|
MMP9 |
IL8 |
4 |
Based on ‘may’ |
Activating interaction |
KEGG: same process |
| MMP1 | MMP3 | 5 | Based on ‘may’ | ||