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Scaffold enrichment factor versus enrichment factor. Average ratio of scaffold enrichment factor (scaffold EF) and the enrichment factor (EF) at 5% of six fingerprints, ECFC0, AP, TT, ECFP4, FCFC4 and lECFP6, as a function of the ratio BMS/actives for the three collection of data sets: MUV (open circles), DUD (open triangles), and ChEMBL (filled circles). The black, dashed line corresponds to y = 1.0.
