Table 1.
Comparison of qualitative and quantitative variables in HIV-infected individuals according to age group, followed in two referral hospitals in the state of Pernambuco, Brazil
Variables | < 40 years (n=351) | ≥ 40 years (n=346) | p-value |
---|---|---|---|
Sociodemographics |
|
|
|
Age (years) – Mean (SD) |
31.8 (4.96) |
47.8 (6.14) |
< 0.001 |
Male (%) |
59.5 |
57.8 |
0.641 |
White (%) |
25.6 |
24.9 |
0.811 |
Stable partner (%) |
19.4 |
24.3 |
0.117 |
Habits |
|
|
|
Smoking (%) |
23.0 |
22.0 |
0.725 |
Alcohol consumption (%) |
40.4 |
35.2 |
0.167 |
Injecting drugs use (%) |
6.0 |
3.8 |
0.368 |
Clinical characteristics |
|
|
|
Diabetes (%) |
0.9 |
6.2 |
< 0.001 |
Lipodystrophy (%) |
31.5 |
39.8 |
0.024 |
Dyslipidemia (%) |
16.1 |
31.7 |
< 0.001 |
Metabolic syndrome (%) |
16.9 |
31.3 |
< 0.001 |
HIV-related characteristics |
|
|
|
Time elapsed since diagnosis HIV (in months -DP) |
40.5 (37.5) |
58.4 (49.6) |
< 0.001 |
CD4 T-lymphocytes baseline - Median (P25 – P75) |
323 (158 – 498) |
258 (94 – 473) |
0.005* |
Viral load baseline - Median (P25 – P75) |
29600 (3341 – 134000) |
57400 (6170 – 205000) |
0.026* |
CD4 T-lymphocytes current - Median (P25 – P75) |
391 (262 – 535) |
383 (242 – 564) |
0.949* |
Viral load, current undetectable (%)** |
31.7 |
46.7 |
0.005 |
HAART duration (in months) Median (P25–P75) |
23.5 (9.9 – 42.6) |
36.3 (17.7 – 65.2) |
< 0.001* |
NNTRI Use (%) |
36.6 |
47.1 |
0.005 |
PI use (%) |
21.7 |
26.9 |
0.112 |
Without HAART (%) |
41.3 |
25.7 |
< 0.001 |
Laboratory tests |
|
|
|
Total cholesterol (mg/dL) - Mean (SD) |
163.5 (40.0) |
189.6 (54.5) |
< 0.001 |
LDL cholesterol (mg/dL) - Mean (SD) |
93.9 (38.8) |
106.7 (40.8) |
0.001 |
HDL cholesterol (mg/dL) - Mean (SD) |
42.2 (13.6) |
43.5 (14.1) |
0.216 |
Triglycerides (mg/dL) - Mean (SD) |
148.8 (102.8) |
204.6 (213.0) |
< 0.001 |
USG of carotid arteries |
|
|
|
Presence of sublinical atherosclerosis (%) |
23.4 |
66.5 |
< 0.001 |
Carotid intima thickness (mm) - Median (SD) | 0.742 (0.084) | 0.841 (0.150) | < 0.001 |
* Kruskal - Wallis test.
** 328 patients with viral load information.