Table 1. Biological process GO terms enriched among methylated genes inA. aegypti.

GO ID	Name	*P -value	Top 10 GO terms
GO:0050789	regulation of biological process	0.001
GO:0065007	biological regulation	0.001
GO:0006350	transcription	0.001
GO:0019222	regulation of metabolic process	0.001
GO:0006139	nucleobase, nucleoside, nucleotide and nucleic acid metabolic process	0.002	A. pisum, A mellifera
GO:0006807	nitrogen compound metabolic process	0.002
GO:0009987	cellular process	0.004	A. pisum, A mellifera
GO:2000112	regulation of cellular macromolecule biosynthetic process	0.010
GO:0031424	Keratinization	0.010
GO:0010556	regulation of macromolecule biosynthetic process	0.012
GO:0080090	regulation of primary metabolic process	0.013
GO:0031323	regulation of cellular metabolic process	0.018
GO:0031326	regulation of cellular biosynthetic process	0.018
GO:0060255	regulation of macromolecule metabolic process	0.021
GO:0044260	cellular macromolecule metabolic process	0.022	A. pisum
GO:0044237	cellular metabolic process	0.024	A. pisum, A mellifera
GO:0006464	protein modification process	0.027
GO:0032774	RNA biosynthetic process	0.036
GO:0010468	regulation of gene expression	0.036
GO:0009889	regulation of biosynthetic process	0.039
GO:0050794	regulation of cellular process	0.043
GO:0030855	epithelial cell differentiation	0.046

^*Benjamini-Hochberg adjusted. Comparison with top 10 enriched categories of methylated genes of A. pisum [49] and A. mellifera [19].