Table 2. Multivariate analysis of TGFβ1 polymorphisms and clinical outcome in NSCLC.
Polymorphism and Genotypes | Overall Survival | Distant Metastasis-Free Survival | ||||
HR | 95%CI | P | HR | 95%CI | P | |
rs1800469 (C–509T) | ||||||
CC (n = 125) | 1.000 | 1.000 | ||||
CT+TT (n = 80) | 1.463 | 1.012–2.114 | 0.043 | 1.601 | 1.042–2.459 | 0.032 |
rs1800471 (G915C) | ||||||
GG (n = 178) | 1.000 | 1.000 | ||||
CG+CC (n = 27) | 0.730 | 0.413–1.291 | 0.280 | 0.758 | 0.395–1.454 | 0.404 |
rs1982073 (T+29C) | ||||||
TT (n = 68) | 1.000 | 1.000 | ||||
CT+CC (n = 137) | 1.271 | 0.873–1.851 | 0.211 | 1.589 | 1.009–2.502 | 0.046 |
Abbreviations: NSCLC, non-small cell lung cancer; HR, hazard ratio; CI, confidence interval.