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. 2013 Jun 19;8(6):e65659. doi: 10.1371/journal.pone.0065659

Table 2. Multivariate analysis of TGFβ1 polymorphisms and clinical outcome in NSCLC.

Polymorphism and Genotypes Overall Survival Distant Metastasis-Free Survival
HR 95%CI P HR 95%CI P
rs1800469 (C–509T)
CC (n = 125) 1.000 1.000
CT+TT (n = 80) 1.463 1.012–2.114 0.043 1.601 1.042–2.459 0.032
rs1800471 (G915C)
GG (n = 178) 1.000 1.000
CG+CC (n = 27) 0.730 0.413–1.291 0.280 0.758 0.395–1.454 0.404
rs1982073 (T+29C)
TT (n = 68) 1.000 1.000
CT+CC (n = 137) 1.271 0.873–1.851 0.211 1.589 1.009–2.502 0.046

Abbreviations: NSCLC, non-small cell lung cancer; HR, hazard ratio; CI, confidence interval.