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. Author manuscript; available in PMC: 2013 Jun 19.
Published in final edited form as: J Alzheimers Dis. 2011;26(4):767–778. doi: 10.3233/JAD-2011-110512

Fig. 1.

Fig. 1

Effect of TBHQ diet on Aβ load in the brain of AβPP/PS1 mice. Two and a half month old male AβPP/PS1 mice were fed with TBHQ or control diet for 6 weeks. Aβ deposits in the brain were revealed by immunohistochemical staining using antibody specific to human Aβ (6E10) (A) and quantified by the histomorphometry system and expressed as percentage of total area of brain (B). The amounts of Aβ40 and Aβ 42, both soluble and insoluble, in the brain were determined by ELISA and calculated based on the total protein content (C&D). *Significantly different from the corresponding control diet fed mice (p < 0.05, n = 5–7).