Fig. 2.
Effects of TBHQ diet on the amounts of full-length AβPP, α-CTF, and β-CTF in the brain of AβPP/PS1 mice. Full-length AβPP (FL-AβPP) and α/β-CTF in the brain of AβPP/PS1 mice were determined by western analyses using 4–20% gradient SDS-PAGE and anti-human Aβ antibody (6E10) or C terminus of human AβPP (CT695) (top panel). The intensities of the bands were semi-quantified by densitometric scanning and normalized by β-actin (bottom panel). *Significantly different from control diet fed mice (p < 0.05, n = 3–5).