Figure 5. Interactive effects of schizophrenia and smoking on Notch4 expression.
Least squares means of log transformed expression relative to GAPDH. Means are adjusted for all other effects in the model. A. Controls with inflammation had significantly increased Notch4 expression compared to those with no inflammation [F(1,87) = 11.1; p = 0.004; fold Δ = 1.8]. This difference in expression did not occur in the schizophrenic subjects. B. Smokers had significantly lower expression than nonsmokers [F(1,87) = 5.85; p = 0.031; fold Δ = 1.3]. Bars are one S.E.M.