(A) Representative Western blot of oligomeric Aβ40 forms extracted from extracellular (Extra), membrane (Mem1 - short exposure; Mem2 - longer exposure), and intracellular (Intra) fractions (cortical tissue) from Tg2576 mice, following i.c.v. injection of 0.2 μg NNC 26-9100 (T) or vehicle (V) (n = 3-4/group). Bar graphs of oligomeric Aβ40 forms identified within (B) extracellular, (C) membrane, and (D) intracellular fractions. Optical densities normalized to respective vehicles. *p < 0.05; ** p < 0.01; *** p < 0.001 (Student’s T-test), values are mean ± S.E.M.