Table 3.
Cox proportional hazards models of osteoporotic fracture risk for older, long-term survivors of early-stage breast cancer versus age-matched comparison women
| Covariates | All fractures | Hip and wrist fractures  | 
||
|---|---|---|---|---|
| HR* | 95% CI | HR* | 95% CI | |
| Model 1: Study site, age | 1.0 | 0.8, 1.2 | 1.0 | 0.8, 1.3 | 
| 
Model 2: Study site, age plus race and body mass index  | 
1.0 | 0.8, 1.2 | 1.0 | 0.8, 1.3 | 
| 
Model 3: Study site, age plus smoking status and comorbid conditions  | 
1.0 | 0.8,1.2 | 1.0 | 0.8, 1.3 | 
| 
Model 4: Study site, age plus drug exposure**  | 
1.1 | 0.9, 1.3 | 1.1 | 0.9, 1.4 | 
| 
Model 5: Study site, age plus all covariates: combined  | 
1.1 | 0.9, 1.3 | 1.1 | 0.9, 1.4 | 
HR = hazard ratio.
Drug exposure detail in Supplemental Table 1