Skip to main content
. Author manuscript; available in PMC: 2014 Jun 1.
Published in final edited form as: J Am Geriatr Soc. 2013 May 6;61(6):888–895. doi: 10.1111/jgs.12269

Table 5.

Cox proportional hazards models of osteoporotic fracture risk for older, long-term survivors of early-stage breast cancer exposed to tamoxifen versus survivors not exposed to tamoxifen.

All fractures Hip and wrist
fractures
Covariates HR* 95% CI HR* 95% CI
Model 1: Study site, age 0.9 0.7, 1.3 0.9 0.7, 1.3
Model 2: Study site, age, race, body
mass index		 0.9 0.7, 1.2 0.9 0.7, 1.3
Model 3: Study site, age, tumor and
treatment variables		 0.9 0.6, 1.2 0.9 0.6, 1.3
Model 4: Study site, age, smoking status,
comorbid conditions		 1.0 0.7, 1.3 1.0 0.7, 1.4
Model 5: Study site, age, drug
exposure** 		0.9 0.6, 1.2 0.9 0.6, 1.3
Model 6: All covariates: Study site, age,
race, body mass index, tumor and
treatment variables, smoking status,
comorbid conditions, and drug exposure		 0.9 0.6, 1.2 0.9 0.6, 1.4
*

HR = hazard ratio.

**

Drug exposure detail in Supplemental Table 1