Figure 2. Effect of LPA on the Proliferation of Pancreatic Cancer Cells.
Equal number of cells (3× 105) BxPC3 (A), Dan-G (B), MDAPanc-28 (C), or PaCa-2 (D) were seeded in 60 mm culture dishes, allowed to adhere overnight and serum-deprived for 24 hours. Cells were then stimulated with 2 μM LPA dissolved in serum-free media or 10 % NBCS. At 24 hour intervals following stimulation, cell were trypsinized and counted on a hemocytometer. Results are expressed as total cell numbers (Mean ± SEM; n = 3).