Skip to main content
. Author manuscript; available in PMC: 2014 Jun 1.
Published in final edited form as: Mol Cancer Res. 2013 Mar 14;11(6):568–578. doi: 10.1158/1541-7786.MCR-12-0710

Figure 3. High-throughput siRNA screening results and corresponding patient gene expression data for PP2A subunits.

Figure 3

(A) PP2A subunit expression in benign prostate epithelia, ADT-resistant primary prostate tumors, and CRPC metastases. (B) Knockdown of PPP2R1A and PPP2R2C induce sufficient growth to reach the significance threshold in both cell lines. Knockdown of other PP2A B-regulatory subunits induced variable effects on proliferation. Dotted lines represent Z=+/−1.96.