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. Author manuscript; available in PMC: 2014 Jun 1.
Published in final edited form as: Mol Cancer Res. 2013 Mar 14;11(6):568–578. doi: 10.1158/1541-7786.MCR-12-0710

Figure 6. PPP2R2C protein expression is downregulated in primary prostate tumors and associates with prostate cancer-specific mortality.

Figure 6

(A – D) IHC for PPP2R2C was performed on a tissue microarray comprised of primary prostate adenocarcinomas acquired by radical prostatectomy. Representative primary tumor cores with mean nuclear intensity (MNI) PPP2R2C staining of 0 (a), 1 (b), 2 (c), and 3 (d) were photographed at 400× original magnification. (E) Patients were subdivided into groups based on the mean nuclear staining intensity (MNI) of PPP2R2C in representative tumor cores. Kaplan-Meier analysis demonstrated a significant difference in survival between patients with high PPP2R2C mean nuclear staining intensity (MNI ≥ 1; blue) and those patients with low PPP2R2C expression (MNI<1; red) (log-rank test; P=0.045).