. Author manuscript; available in PMC: 2014 Feb 25.

Published in final edited form as: Chem Biol Interact. 2012 Dec 13;202(0):11–21. doi: 10.1016/j.cbi.2012.11.022

Table 1.

ALDH1B1 and ALDH1A genes and enzymes in selected vertebrate species.

Animal	Species	ALDH gene	RefSeq ID¹ Ensembl/NCBI	GenBank ID	UNIPROT ID	Amino acids	Chromosome location (coding exons)	Coding exons (strand)	Gene size coding exon(s)	Subunit MW	Gene expression levels	Mitochondrial leader sequence	% amino acid sequence identity with human isozyme
Animal	Species	ALDH gene	RefSeq ID¹ Ensembl/NCBI	GenBank ID	UNIPROT ID	Amino acids	Chromosome location (coding exons)	Coding exons (strand)	Gene size coding exon(s)	Subunit MW	Gene expression levels	Mitochondrial leader sequence	ALDH2	ALDH1B1	ALDH1A1
Human	Homo sapiens	1B1	NM_000692	BC001619	P30837	517	9:38,385,746–38,387,296	1 (+ve)	1551	57,206	2.2	1…17	72	100	64
Chimpanzee	Pan troglodytes	1B1	XP_001170562 ^a	AK306189	na	517	9:38,899,005–38,900,555	1 (+ve)	1551	57,276	na	1…17	72	99	64
Gorilla	Gorilla gorilla	1B1	ENSGGOT13385^b	Na	na	517	9:39,239,653–39,241,203	1 (+ve)	1551	57,265	na	1…17	71	98	64
Orangutan	Pongo abelii	1B1	NM_001134104	CR860576	Q5R6B5	517	9:23,179,163–23,180,713	1 (−ve)	1551	57,261	na	1…17	71	98	64
Gibbon	Nomascus leucogenys	1B1	XP_003263524 ^a	na	na	inc	GL397291:19,434,443–19,436,340^{^}	1 (−ve)	inc	inc	na	1…17	71	98	63
Rhesus	Macaca mulatta	1B1	XP_001114412 ^a	EHH23951	F7H5N9	517	15:39,015,754–39,017,304	1 (−ve)	1551	57,175	na	1…17	71	98	64
Marmoset	Callithrix jacchus	1B1	XP_002743154 ^a	Na	na	514	1:140,345,262–140,346,964	2 (+ve)	1703	56,987	na	1…12	71	96	64
Mouse	Mus musculus	1b1	NM_028270	BC020001	Q9CZS1	519	4:45,815,336–45,816,892	1 (+ve)	1557	57,553	2.8	1…19	72	94	65
Rat	Rattus norvegicus	1b1	NM_001011975	BC081884	Q66HF8	519	5:62,314,156–62,315,712	1 (+ve)	1557	57,625	0.1	1…19	71	93	65
Pig	Sus scrofa	1B1	XP_003353634 ^a	AK347304	na	517	1: 250,617,521–250,619,071	1 (+ve)	1551	57,535	na	1…17	71	94	64
Dog	Canis lupus familiaris	1B1	XP_538742 ^a	na	na	520	11:57,607,718–57,609,277	1 (+ve)	1560	57,693	na	1…19	71	94	64
Panda	Ailuropoda melanoleuca	1B1	XP_002914982 ^a	na	na	517	GL192407.1:2,469,008–2,470,558^{^}	1 (−ve)	1551	57,604	na	1…16	69	93	64
Horse	Equus caballus	1B1	XP_001915212 ^a	na	na	inc	25:3,341,847–3,343,364	1 (+ve)	1518	inc	na	inc	63	84	58
Cow	Bos taurus	1B1	XP_599364 ^a	na	na	inc	8:62,891,068–62,892,600	1 (+ve)	1533	inc	na	inc	65	85	59
Opossum	Monodelphis domestica	1B1	XP_003341640 ^a	na	na	517	6:31,302,337–31,303,887	1 (+ve)	1551	57,208	na	1…12	70	88	66
Tasmanian devil	Sarcophilis harrisii	1B1	XP_003761415 ^a	na	na	517	GL841485:1,411,647–1,413,197	1 (+ve)	1551	57,180	na	1…16	71	89	66
Platypus	Ornithorynchus anatinus	1B1	XP_001519422 ^a	na	na	517	Contig15042:5,629–7,179^*	1 (−ve)	1551	57,667	na	1…18	70	90	65
Frog	Xenopus tropicalis	1B1	XP_002940309 ^a	na	na	520	GL173,226 ++ 17640–19,124^{^}	1 (+ve)	1560	57,008	na	1…17	67	76	63
Human	Homo sapiens	1A1	NM_000689	AK293176	P00352	501	9:74,705,947–74,757,736	13 (−ve)	52,656	54,862	4.4	na	68	65	100
Human	Homo sapiens	1A2	NM_003888	BC030589	O94788	518	15:56,034,690–56,145,140	13 (−ve)	112,500	56,724	2.6	na	67	67	73
Human	Homo sapiens	1A3	NM_000693	BC069274	P47895	512	15:101,420,009–101,456,830	13 (+ve)	36,822	56,108	3.5	na	66	64	71

na: Not available; +ve indicates positive strand; −ve indicates negative strand.

RefSeq refers to the NCBI reference sequence.

Predicted NCBI sequence.

Gorilla sequence was derived from BLAT using the UCSC web browser [19].

^{^}

Gene scaffold ID.

Refers to Contig ID; bps refers to base pairs of nucleotide sequence; Inc. an incomplete genome sequence was available for analysis; gene expression levels for ALDH1B1 and ALDH1A genes are taken from [20].