Table 1.
UKPDS | ACCORD [31] | ADVANCE [32] | VADT [33] | |
---|---|---|---|---|
Follow-up [30] | ||||
Number of patients | 3,277 | 10,251 | 11,140 | 1,791 |
Mean (SD) age, years | 62.0 (8) | 62.2 (6.8) | 66.0 (6) | 60.5 (9) |
Duration of diabetes on entry, years | Newly diagnosed | 10.0 | 8.0 | 11.5 |
Cardiovascular outcome | Benefit | Harm | No benefit | No benefit |
ACCORD Action to Control Cardiovascular Risk in Diabetes, ADVANCE Action in Diabetes and Vascular Disease: Preterax and Diamicron MR Controlled Evaluation, UKPDS UK Prospective Diabetes Study, VADT Veterans Affairs Diabetes Trial