Table 1.
Impact of an ABC on patient satisfaction and quality of life
| References | Study design | Objectives | Results |
|---|---|---|---|
| Sussman et al. [29] | Multicenter study comparing manual versus ABC-assisted calculations of insulin doses | Evaluation of error frequency when insulin dosages calculated either manually or with an ABC | Significant reduction of errors when doses calculated with an ABC (P < 0.001) |
| 205 MDI-treated patients | Improved confidence and preference of using an ABC (P < 0.0001) | ||
| 47.6% type 1 diabetes; 52.4% type 2 diabetes; 104 non-CC; 101 CC | Increased adherence may optimize the use of meal-time insulin | ||
| Glaser et al. [31] | 12-month randomized control trial comparing an IDC device to conventional methods for insulin doses | Impact of an ABC on metabolic control | Higher rate of calculation errors with conventional methods |
| 83 MDI- or CSII-treated type 1 diabetes adolescents | Impact of an ABC on treatment satisfaction, regimen adherence, and quality of life | Improvement in treatment satisfaction, adherence, and quality of life among ABC users | |
| No change in HbA1c among ABC users | |||
| Shashaj et al. [32] | 2-week crossover study comparing an ABC (Bolus Wizard) to conventional methods for insulin doses | Improvement of pre- and postprandial glycemic control | Significant reduction in pre- and 2-h postprandial BG levels and in the number of correction boluses (P < 0.05) |
| 36 CSII-treated type 1 diabetes adolescents | Treatment satisfaction | Higher satisfaction level among ABC users | |
| Gross et al. [33] | 7-day crossover study comparing an ABC to conventional methods for insulin doses | Improvement of postprandial BG levels | Less correction boluses to control postprandial hyperglycemia when using the ABC (P < 0.05) |
| 49 CSII-treated type 1 diabetes subjects | Less supplemental glucose to raise low BG levels when using the ABC (P < 0.05) | ||
| Decreased average deviation of 2-h postprandial BG levels | |||
| ABC easy to use and confidence in advised insulin doses |
ABC automated bolus calculator, BG blood glucose, CC carbohydrate counters, CSII continuous subcutaneous insulin infusion, HbA 1c glycated hemoglobin, IDC insulin dosage calculation, MDI multiple daily injection