Table 1.

Demographic and clinical characteristics at double-blind baseline (safety set, both studies)

Parameter	Study SP516 (N = 395)	Study SP715 (N = 258)
Age in years, mean ± SD (range)	64.4 ± 9.2 (39–84)	66.4 ± 9.6 (34–88)
Male, N (%)	251 (64)	173 (67)
Caucasian, N (%)	385 (97)	240 (93)
Time since first diagnosis in years, mean ± SD (range)	8.5 ± 4.6 (3–29)	7. 8 ± 4.5 (2–24)
UPDRS part II score in years, mean ± SD (range)	12.3 ± 5.9 (0–33)	12.6 ± 6.4 (0–36)
UPDRS part III score in yeras, mean ± SD (range)	27.0 ± 11.7 (1–65)	26.1 ± 13.8 (0–83)

SD standard deviation, UPDRS unified Parkinson’s disease rating scale