Figure 1.

Meta-regression of percent of women on OR for incident diabetes. Only trials examining statin vs. nonstatin placebo or control arms are represented. The percent of women in each trial was obtained from the index publications. When available, the percent of nondiabetic women was used (HPS, LIPID); otherwise, the percent of women in the trial as a whole was used. ORs (natural log-transformed, ln) for diabetes were obtained from the Sattar et al. meta-analysis (3) and from Waters et al. for SPARCL (6). The error bars represent the 95% CIs. The adjusted HR for diabetes from the WHI is plotted for comparison (open circle); its data were not used in the regression calculation.