Table III.
Bivariate analysis of 30 day major postoperative complications after non-obstetric antenatal surgery by preoperative risk factor.
| 30 day major complication (n=115) |
No major complication (n=1,854) |
p-value | |
|---|---|---|---|
| Age (years, mean ±SD) | 31.87 ± 7.67 | 28.46 ± 6.42 | <.001 |
|
| |||
| Race | |||
| White | 70(60.87) | 1,231(66.40) | 0.22 |
|
| |||
| Ethnicity | |||
| Hispanic | 13(11.30) | 331(17.85) | 0.073 |
|
| |||
| Current smoker | 23(20.00) | 387(20.87) | 0.823 |
|
| |||
| Body mass index (kg/m2, mean, ±SD) | 29.90 ± 7.00 | 29.33 ± 7.53 | 0.439 |
|
| |||
| Previous procedure within 30 days | 12 (10.4) | 34 (1.8) | <.001 |
|
| |||
| Hypertension | 9(7.83) | 59(3.18) | 0.008 |
|
| |||
| Diabetes mellitus | 7(6.09) | 44(2.37) | 0.015 |
|
| |||
| History of CVA with neurologic deficit | 2(1.74) | 5(0.27) | 0.059 |
|
| |||
| Steroid use for chronic condition | 3(2.61) | 20(1.08) | 0.147 |
|
| |||
| Preoperative systemic infection | 51 (44.4) | 439 (23.7) | <.001 |
| SIRS | 33 (28.7) | 384 (20.7) | |
| Sepsis | 13 (11.3) | 52 (2.8) | |
| Septic Shock | 5 (4.4) | 3 (0.2) | |
|
| |||
| Known bleeding disorder | 7(6.09) | 30(1.62) | 0.001 |
|
| |||
| Current pneumonia | 3(2.61) | 6(0.32) | 0.013 |
|
| |||
| Preoperative blood transfusion > 4 units | 3(2.61) | 4(0.22) | 0.006 |
|
| |||
| Prior myocardial infarction within 6 months | 3(2.61) | 6 (0.32) | 0.013 |
|
| |||
| New or exacerbated congestive heart failure | 2(1.74) | 5(0.27) | 0.059 |
|
| |||
| Prior percutaneous coronary intervention | 3(2.61) | 4(0.22) | 0.006 |
|
| |||
| Prior cardiac surgery | 4(3.48) | 8(0.43) | 0.004 |
|
| |||
| Angina within 30 days of surgery | 3(2.61) | 4(0.22) | 0.006 |
|
| |||
| New York Heart Class III or IV | 13(11.30) | 33(1.78) | <.001 |
|
| |||
| Chronic obstructive pulmonary disease | 1(0.87) | 4(0.22) | 0.26 |
|
| |||
| Ventilator dependency | 12(10.43) | 6(0.32) | <.001 |
|
| |||
| Acute or chronic dialysis | 5(4.35) | 11(0.59) | 0.002 |
|
| |||
| Acute or chronic renal failure | 3(2.61) | 6(0.32) | 0.013 |
|
| |||
| Ascites | 7(6.09) | 16(0.86) | <.001 |
|
| |||
| Esophageal varicies | 1(0.87) | 4(0.22) | 0.26 |
|
| |||
| Unintentional weight loss of > 10% in last 6 months | 2(1.74) | 15(0.81) | 0.261 |
|
| |||
| Functional status(dependent/partially dependent for ADLs) | 20(17.39) | 29(1.56) | <.001 |
|
| |||
| Current Cancer | 2(1.74) | 11(0.59) | 0.174 |
| Current radiation therapy within 30 days | 1(0.87) | 4(0.22) | |
| Current chemotherapy within 30 days | 1(0.87) | 8(0.43) | |
| Known CNS tumor | 1(0.87) | 5(0.27) | |
| Disseminated cancer | 2(1.74) | 7(0.38) | |
|
| |||
| ASA | <.001 | ||
| Class 1 or 2 | 73(63.48) | 1,631(87.97) | |
| Class 3 | 25(21.74) | 219(11.81) | |
| Class 4 | 13(11.30) | 4(0.22) | |
| Class 5 | 4(3.48) | 0 | |
|
| |||
| Emergency surgery | 65(56.52) | 915(49.35) | 0.136 |
|
| |||
| Work relative value unit (mean, ±SD) | 14.40 ± 7.77 | 10.97 ± 4.53 | <.001 |
|
| |||
| Type of anesthesia (general) | 109(94.78) | 1,648(88.89) | 0.048 |
|
| |||
| Operative time | <.001 | ||
| < 1 hour | 32(27.83) | 1,136(61.27) | |
| 1-2 hours | 54(46.96) | 546(29.45) | |
| 2-3 hours | 17(14.78) | 113(6.09) | 113(6.09) |
| 3-4 hours | 7(6.09) | 44(2.37) | |
| >4 hours | 5(4.35) | 15(0.81) | |
|
| |||
| Wound class | <.001 | ||
| 1-Clean | 35(30.43) | 388(20.93) | |
| 2-Clean/contaminated | 35(30.43) | 781(42.13) | |
| 3-contaiminated | 14(12.17) | 428(23.09) | |
| 4-dirty | 31(26.96) | 257(13.86) | |
All values listed as n(%) unless otherwise specified
SD = standard deviation
ADLs = activities of daily living
ASA = American Society of Anesthesiologist
CVA = cerebrovascular accident
SIRS = systemic inflammatory response syndrome