. Author manuscript; available in PMC: 2014 Jan 1.

Published in final edited form as: Arthritis Rheum. 2013 Jan;65(1):226–235. doi: 10.1002/art.37742

Table 4.

Correlation of plasma IFN inducible chemokines with disease severity

	IP-10				I-TAC				IP-10 & I-TAC

	Cor	p_u	p_m†	p_mc¶	Cor	p_u	p_m†	p_mc¶	Cor	p_u	p_m†	p_mc‡
FVC	−0.08	0.272	0.427	0.854	−0.21	0.003	0.005	0.010	−0.17	0.013	0.024	0.048
DLCO	−0.10	0.160	0.038	0.076	−0.21	0.002	<0.001	<.001	−0.18	0.008	0.001	0.002
CK	0.12	0.077	0.189	0.378	0.23	<0.001	0.001	0.002	0.21	0.002	0.004	0.008
mRSS	0.16	0.014	0.027	0.054	0.04	0.502	0.582	1	0.1	0.125	0.161	0.322
Skin^*	0.16	0.014	0.013	0.026	0.04	0.542	0.412	0.824	0.12	0.073	0.043	0.086
Muscle^*	0.19	0.003	0.004	0.008	0.15	0.02	0.032	0.064	0.18	0.006	0.011	0.022
GI^*	0.02	0.779	0.656	1	0.07	0.29	0.191	0.382	0.06	0.38	0.270	0.540
Lung^*	0.08	0.207	0.106	0.212	0.15	0.018	0.008	0.016	0.15	0.021	0.009	0.018
Heart^*	0.04	0.552	0.381	0.762	0.02	0.811	0.600	1	0.04	0.565	0.377	0.754
Kidney^*	−0.07	0.257	0.144	0.288	0.03	0.604	0.768	1	0.01	0.878	0.876	1.000
Joint^*	0.13	0.051	0.030	0.060	0.06	0.340	0.327	0.654	0.10	0.106	0.080	0.160

Components of Medsger Severity Index.

^†

Multivariate model after adjustment for age at enrollment, gender, ethnicity, disease duration, and treatment with immunosuppressive agents

Abbreviations: FVC: Percent predicted forced vital capacity; DLco: Percent predicted diffusing capacity; mRSS: modified Rodnan Skin Score; CK: Creatine kinase. Cor: Correlation coefficient; p_u: p value from univariable model; p_m^† : p value from multivariable model after adjustment for age at enrollment, gender, ethnicity, disease duration, and treatment with immunosuppressive agents; p_m‡: p value from multivariable model with multiple comparison correction.