Table 1.

Multivariable logistic analyses for serum miR-21 levels and various diagnostic factors in patients with colorectal cancer (CRC) and adenomas*

Variables	OR (95% CI)	P
CRC patients vs control subjects
Age, >67 y vs ≤67 y†	1.69 (0.73 to 3.92)	.22
Sex, female vs male	1.81 (0.78 to 4.22)	.17
miR-21 in serum, >0.0019 vs ≤0.0019‡	43.3 (17.53 to 107.13)	<.001
Adenoma patients vs control subjects
Age, >67 y vs ≤67 y†	0.54 (0.21 to 1.39)	.20
Sex, female vs male	1.32 (0.53 to 3.34)	.55
miR-21 in serum, >0.0013 vs ≤0.0013‡	6.62 (2.63 to 16.88)	<.001

* CI = confidence interval; OR = odds ratio.

† Median age was 67 years.

‡ The cutoff values of serum miR-21 in CRC patients vs control subjects and adenoma patients vs control subjects were derived by receive operating characteristic curves with Youden’s index.