Table 3.
Statistical analysis of the results obtained in the test of Rod-123 accumulation in the lymphocyte cultures
| Tested compounds | Rod-123 accumulation [FAU] | ||||||
|---|---|---|---|---|---|---|---|
| mean; n = 5 | SD | minimal value | maximal value | median | p | ||
| FPh | 85 | 6.26 | 78 | 94 | 86 | 0.08 | |
| analogues | 1a | 93 | 9.94 | 83 | 105 | 89 | 0.021 |
| 1b | 98 | 13.58 | 84 | 113 | 96 | 0.032 | |
| 1c | 89 | 8.87 | 74 | 97 | 90 | 0.059 | |
| 1d | 93 | 6.88 | 85 | 102 | 91 | 0.001 | |
| 1e | 89 | 6.06 | 79 | 95 | 90 | 0.023 | |
| 1f | 90 | 4.44 | 84 | 95 | 90 | 0.005 | |
| 1g | 91 | 7.40 | 83 | 101 | 89 | 0.015 | |
| 1h | 89 | 7.19 | 81 | 98 | 88 | 0.065 | |
| 2c | 82 | 4.56 | 77 | 89 | 81 | 0.24 | |
| 3a | 75 | 7.46 | 69 | 88 | 72 | 0.66 | |
| 3b | 83 | 7.60 | 74 | 92 | 81 | 0.24 | |
| 3c | 86 | 8.56 | 74 | 96 | 86 | 0.045 | |
| 3e | 84 | 9.34 | 74 | 95 | 84 | 0.22 | |
| 3f | 101 | 6.83 | 94 | 109 | 98 | 0.006 | |
| 3f | 101 | 6.83 | 94 | 109 | 98 | 0.006 | |
| 3g | 79 | 10.26 | 65 | 87 | 86 | 0.67 | |
| 3h | 94 | 9.73 | 82 | 109 | 93 | 0.043 | |
| 3i | 104 | 8.93 | 91 | 112 | 109 | 0.003 | |
| control cultures | 77 | 4.66 | 71 | 84 | 77 | – | |