TABLE 2.

Nucleotide and amino acid sequence comparisons of HEV-B strains to one another and to representatives of HEV-A, HEV-C, and HEV-D^a

Regionb	% Identity (range)
	HEV-B	HEV-A (CAV16)	HEV-C (PV1)	HEV-D (EV70)
5′-NTR	76.9-95.0	79.2-88.0	68.2-73.0	68.0-72.9
P1 (capsid)	68.5-87.0	47.7-50.5	54.8-58.0	46.9-50.5
VP4	69.6-100	53.6-60.9	59.4-71.0	46.4-58.0
VP2	66.0-86.0	51.6-57.6	54.2-61.7	52.6-58.9
VP3	65.8-87.0	44.4-51.1	53.8-61.8	42.7-50.4
VP1	56.4-83.0	36.0-46.0	45.0-51.4	38.2-45.3
P2	92.9-99.0	62.7-66.6	57.9-59.5	63.0-64.5
2A	82.0-97.0	65.3-78.0	52.3-57.7	56.6-60.1
2B	91.9-100	52.5-54.5	47.4-51.5	58.6-62.6
2C	95.4-100	64.3-65.5	61.7-62.9	65.0-67.5
P3	94.3-99.0	61.8-63.2	67.7-69.1	71.1-72.7
3AB	88.3-100	53.7-56.5	56.0-59.6	66.7-70.3
3C	92.9-100	55.7-56.8	59.6-61.2	62.3-63.9
3D	94.6-99.0	66.0-67.7	73.5-74.8	75.5-76.8
3′-NTR	70.3-99.0	41.7-51.8	45.1-62.3	42.7-51.2

^aSequences for representatives of other species were obtained from GenBank. HEV-A: CAV16, accession no. U05876. HEV-C: PV1, accession no. J02281. HEV-D: EV70, accession no. D00820.

^b5′-NTR and 3′-NTR are nucleotide sequence comparisons; all others are amino acid sequence comparisons.