Table 1.

Alteration	Shear	Strain
Proliferation	(Li et al., 2004)	(Kaspar et al., 2002; Boutahar et al., 2004)
Differentiation:
RUNX2,   Osterix	(Li et al., 2004)	Rubin J., unpub data
β-catenin	(Norvell et al., 2004)
Remodeling:
RANKL	(Kim and Jacobs, 2005)	(Rubin et al., 2003)
Osteoprotegerin	Jacobs C, unpub data	Unaffected (Rubin et al., 2002c)
Cytokine
secretion:
PGE, NO	(Smalt et al., 1997a; Klein-Nulend et al., 1998; McAllister and Frangos, 1999)	(Rubin et al., 2003) (Zaman et al., 1999)
Extracellular
matrix:
Osteopontin	(You et al., 2001)	(Toma et al., 1997; Ziambaras et al., 1998)
Collagenase-3		(Yang et al., 2004)