. Author manuscript; available in PMC: 2014 May 1.

Published in final edited form as: Genet Med. 2012 Dec 6;15(5):361–367. doi: 10.1038/gim.2012.109

Table 1.

Characteristics of participants

	Training set		Test set
	Cases (n = 543)	Controls (n = 435)	Cases (n = 594)	Controls (n = 395)
Age in years (mean ± SE)	67.5 ± 0.47	65.9 ± 0.58	67.1 ± 0.44	65.0 ± 0.59
Male sex (%)	66.9	37.9	69.4	36.7
Ever smoker (%)	46.6	44.6	45.8	48.9
Self-reported family history (%)
Unknown	11.4	10.3	9.9	10.1
First-degree relative	9.6	3.5	13.3	3.8
Second-degree relative	7.7	3.0	5.2	3.5
Third-degree relative	2.0	1.2	2.5	1.0
Risk allele score (mean ± SE)
Model 3/5	0.07 ± 0.01	−0.04 ± 0.02	0.07 ± 0.02	−0.02 ± 0.02
Model 4	0.18 ± 0.03	−0.19 ± 0.03	0.09 ± 0.03	−0.13 ± 0.03