Table 2. Comparison between the prepubertal response group and the pubertal response group.
A | GnRH stimulation test | ||
Prepubertal | Pubertal | p value | |
Cases within 1 yr | 8 | 3 | <0.01 |
Cases after 1 yr | 0 | 10 | |
Total | 8 | 13 | |
B | GnRH stimulation test | ||
Prepubertal | Pubertal | p value | |
CA at breast development (yr) | 6.9 ± 0.6 | 6.9 ± 0.7 | NS |
BA/CA ratio | 1.19 ± 0.12 | 1.25 ± 0.08 | NS |
Height (SD) | + 0.39 ± 1.12 | + 0.95 ± 0.90 | NS |
Obesity (%) | + 9.2 ± 9.7 | + 18.3 ± 19.4 | NS |
Gestational age (w) | 38.4 ± 2.1 | 38.3 ± 2.8 | NS |
Birth body weight (g) | 2,823 ± 709 | 2,726 ± 752 | NS |
Target height (cm) | 154.0 ± 5.2 | 155.5 ±.4 | NS |
Mother’s menarche (yr) | 11.6 ± 1.3 | 11.5 ± 1.0 | NS |
IGF-I (ng/ml) | 214 ± 64 | 418 ± 148 | p<0.01 |
Estrogen (pg/ml) | 9 ± 4 | 22 ± 13 | p<0.01 |
DHEA-S (µg/dl) | 37 ± 37 | 56 ± 25 | NS |
Data are shown as means ± SD. A: Duration from breast development, B: Clinical characteristics and laboratory data.