Figure 9.

Effects of NAGly on endothelial hyperpolarization and endothelium-dependent relaxation to Ach in excised rat aorta. (A) Representative recording showing the effect of NAGly (3 μM) on the hyperpolarizing response to Ach (2 μM) in rat aortic endothelium (n = 3). (B) Representative recording showing the effect 5 μM NAGly on the relaxation of rat aortic rings produced by Ach (2 μM; n = 4). (C) Representative recording showing the effect of NAGly on norepinephrine-induced contraction of de-endothelized rat aortic ring (n = 4).