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. 2004 Jan;78(2):1006–1011. doi: 10.1128/JVI.78.2.1006-1011.2004

FIG. 4.

FIG. 4.

Resistance of NIH 3T3 cells to SIVmac is saturable by SIVmac but not B-MLV particles. (A) Inhibition of SIVmac-GFP restriction in NIH 3T3 cells by SIVmac VLPs. NIH 3T3 cells were inoculated with a fixed and equivalent dose (as measured on MDTF cells) of N-MLV, B-MLV, or SIVmac GFP reporter viruses, in the presence of increasing amounts of SIVmac VLPs. The VLP dose is given in nanograms of reverse transcriptase per well. (B) B-MLV particles cannot inhibit restriction to SIVmac infection in NIH 3T3 cells. NIH 3T3 cells were inoculated with a fixed and equivalent dose (as measured on Fv1-null MDTF cells) of B-MLV or SIVmac GFP reporter viruses, in the presence of increasing amounts of N-neo or B-neo virus particles. The inhibiting (neo) virus dose is given as the titer (in infectious units [i.u.]) as measured on MDTF cells.