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. Author manuscript; available in PMC: 2013 Jun 20.
Published in final edited form as: J Thromb Haemost. 2011 Feb;9(2):350–360. doi: 10.1111/j.1538-7836.2010.04156.x

Fig. 6. The shortened time to occlusion in COX-1+/− COX-2−/− mice is normalized by the administration of an inhibitory antibody to mouse PAI-1.

Fig. 6

Wild type (WT) and COX-1+/− COX-2−/− mice were given a inhibitory antibody to mouse PAI-1 prior to the administration of Rose Bengal in the carotid artery injury model. The time to occlusion was measured. *P<.001 compared with wild typecontrol mice; **P<.001 compared with COX-1+/− COX-2−/− control mice. Data are means ± SD of 13 mice per group for wild type control, 6 for wild type + anti PAI-1, 13 for COX-1+/− COX-2−/− control, 9 for COX-1+/− COX-2−/− anti-PAI-1 mice.