Table 1.

Demographic information of all samples

	Derivation sample		Validation sample
	ADNI NC	ADNI AD	BAC NC	UCSF AD
Demographics
Number of subjects	39	50	72	19
Age at MRI (years)	78.0 (6.4) 62–94	76.5 (7.4) 59–88	74.9 (5.7) 63–88	67.8 (9.7)*** 58–89
Number of women	17 (44%)	20 (40%)	48 (67%)	9 (47%)
Education (years)	15.8 (2.8) 9–20	14.6 (3.1)** 6–20	17.0 (1.9) 12–20	16.4 (3.2) 9–22
Measurements
Δ time (MRI–FDG) (years)	0.1 (0.1)	0.1 (0.1)	0.2 (0.4)	0.4 (0.5)
Δ time (FDG-Aβ)	florbetapir, 3.1 years (2.1 years)	n.a.	PIB, 0.0 d	n.a.
	CSF Aβ, 23.2 d (35.6 d)	n.a.		n.a.
Δ time (NTS-MRI) (years)	0.1 (0.1)	0.1 (0.0)	0.3 (0.2)	0.3 (0.4)
Biomarkers
N of Aβ-negative (−) or Aβ-positive (+)	29 florbetapir−, 10 CSF Aβ−	n.a.	47 PIB−, 25 PIB+	n.a.
APOE ε4 carrier	6 (15%)	36 (72%)	22 (31%)	10 (53%), missing: 3
Clinical cognitive status
MMSE	29.2 (1.2)	23.4 (2.2)*	28.8 (1.4)	20.3 (6.6)***
CDR (if available) 0/0.5/1/3	39/0/0	0/16/34	n.a.	1/5/10/1, missing: 2

Values are given as the mean (SD) and span, if helpful. NTS, Neuropsychological test session; Δ, absolute difference; MMSE, mini mental status examination; CDR, clinical rating scale; n.a., not available.

*p <0.05;

**p <0.1 comparison between ADNI NC and ADNI AD;

***p <0.05, comparison between BAC NC and UCSF AD.