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. 2013 Feb 23;14:64. doi: 10.1186/1471-2105-14-64

Table 1.

Performance of the classifiers under the alternative hypothesis with large class-imbalance (k1 = 0.9) and moderate differences between classes (μ2 =1 )

Method
λa
#, % info
# non-info [%]
FDR
PA1
PA2
g-means
AUC
          (n1 = 90) (n2 = 10)    
PAM
0.05
99.94
9184.1 [92.77]
0.99
0.95
0.11
0.31
0.6
 
(0.08)
(0.87)
(1136.28)
(0.00)
(0.02)
(0.05)
(0.07)
(0.04)
GM-PAM
1.29
58.81
602.1 [6.08]
0.62
0.63
0.64
0.62
0.69
 
(0.51)
(43.6)
(1004.73)
(0.38)
(0.1)
(0.16)
(0.08)
(0.1)
ALP
0.07
99.96
9004.2 [90.95]
0.99
0.95
0.11
0.3
0.61
 
(0.19)
(0.54)
(2232.18)
(0.01)
(0.03)
(0.07)
(0.08)
(0.04)
GM-ALP
3.76
63.08
408.8 [4.13]
0.59
0.67
0.61
0.63
0.68
 
(2.21)
(41.09)
(816.3)
(0.36)
(0.1)
(0.17)
(0.09)
(0.09)
AHP
0.36
96.89
6438.9 [65.04]
0.95
0.94
0.14
0.34
0.62
 
(1.57)
(12.84)
(4235.52)
(0.11)
(0.04)
(0.1)
(0.1)
(0.05)
GM-AHP
5.29
37.45
266.5 [2.69]
0.42
0.78
0.5
0.6
0.69
  (3.94) (37.96) (1275.07) (0.4) (0.08) (0.18) (0.12) (0.1)

The table reports the estimated optimal threshold (λ), the number [%] of active non-informative variables (# non-info [%], selected out of 9,900 non-informative variables) and the number (also equal to %) of active informative variables (#, % info, selected out of 100 informative variables, equal to 100(1-false negative rate)), false discovery rate (FDR, # non-info/(# active)), class specific predictive accuracies, g-means and AUC, averaged over 500 repetitions; standard deviations are reported in brackets. The simulation settings are the same as in Figure 2. a For AHP and GM-AHP only λθ was optimized while λγ was set to zero.