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. 2013 Jun 19;54(6):4197–4207. doi: 10.1167/iovs.13-11608

Figure 5.

Figure 5

The effect of systemic administration of GW0742 and GSK0660 on OIR-induced NV. (A) Representative images of retinal quadrants in rats treated with vehicle by oral gavage, 10 mg/kg GW0742 by oral gavage, and 1.0 mg/kg GSK0660 by intraperitoneal injection. (B) GW0742 was administered by oral gavage (1.0 and 10 mg/kg) and GSK0660 by intraperitoneal injection (0.2 and 1.0 mg/kg). GW0742 significantly increased the NV area at the highest concentration tested, whereas GSK0660 significantly decreased the NV area at both concentrations tested. Each bar represents the mean ± SEM.