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Combination therapy with rapamycin improves survival in half of the BTIC lines in vivo. Kaplan–Meier plots of various BTICs treated with DV, rapamycin (2.5 mg/kg/daily), MYXV (2 injections of 5 × 106 FFUs/mouse), or both. (A) Survival of BT025-bearing mice after treatment. (B) Survival of BT042-bearing mice after treatment. (C) Survival of BT012-bearing mice after treatment. (D) Survival of BT048-bearing mice after treatment. Arrows indicate time of viral inoculation.
