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Correlations between MSH2 and MLH1. In cases with progression-free survival (PFS) < 4, the correlation between MSH2 and MLH1 (A) demonstrated an R2 of 0.1178. In contrast, a more positively inflected correlation between MSH2 and MLH1 was seen in cases with PFS ≥ 4 had an R2 of 0.3847.