Skip to main content
. 2009 Apr 29;29(17):5654–5665. doi: 10.1523/JNEUROSCI.5978-08.2009

Figure 4.

Figure 4.

Unitary conductance of heteromeric Slick-EE/Slack-B channels is distinct from that of homomeric Slick-EE or Slack-B channels. A–C, Representative single-channel activities recorded from oocytes expressing Slick-EE alone (A) or coinjected with equal amounts of cRNA for Slick-EE and Slack B (B), or expressing Slack-B alone (C). All current traces were recorded at −40 mV from excised inside-out patches. The top and bottom traces in A and B are from separate experiments. The closed state (C) and openings levels corresponding to one to three open channels (O1–O3) are shown. D, All points amplitude histograms are shown for (A, top; B, center; C, bottom). The vertical lines align closed states (C) and single open states (O) for homomeric Slack-B channels, heteromeric channels (Het), and homomeric Slick-EE channels. E, Unitary current–voltage relationships for homomeric Slick-EE channels (∼495 pS), Slack-B channels (∼180 pS), and heteromeric Slick-EE/Slack-B channels (∼324 pS).