Table 5.
Summary of serum Cytokines values at screening, 1 month & 6 month follow-up after BM-MSC implantation
|
Test |
Screening |
1 month |
6 months |
Normal range (pg/ml) |
|||
|---|---|---|---|---|---|---|---|
| |
BM-MSC arm |
Placebo |
BM-MSC arm |
Placebo |
BM-MSC arm |
Placebo |
|
| |
N = 10 |
N = 10 |
N = 9 |
N = 10 |
N = 7 |
N = 10 |
|
| Mean (SD) | Mean (SD) | Mean (SD) | Mean (SD) | Mean (SD) | Mean (SD) | ||
| Gamma - Interferon (pg/ml) |
24.4(13.35) |
23.1(24.07) |
37.8 (34.35) |
20(24.67) |
9.1(6.34) |
6.6(3.57) |
0.01 - 168 |
| Interleukin - 1 (pg/ml) |
22.6(14.73) |
22.9(15.31) |
33.1(23.59) |
22.9(21.73) |
26.6(29.28) |
10(3.26) |
0 - 400 |
| Tumor Necrosis Factor - alpha (pg/ml) | 14.2(9.16) | 13.8(10.11) | 16.6(6.16) | 15.7(7.98) | 11.4(11.65) | 4.4(2.47) | 0 – 3.22 |